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Dr. Deirdre Mc Namara

Assoc Prof Consultant (Clinical Medicine)

 


  Colon Cancer Screening   CROHNS DISEASE   HELICOBACTER PYLORI INFECTION   Small Bowel Angiodysplasia
Details Date
Member National Endoscopy Training Committee 2018
Member Tallaght Hospital / St. James's Hospital Joint Research Ethics Committee (REC). 2012
Member National Clostridium Difficile Guidelines Subgroup Health Protection Surveillance Centre 2012
Endoscopy Lead Clinician for Grampian, Diagnostics Collaborative Programme,Scottish Executive 2006
Deputy Editor Burden of Gastrointestinal Disease in Europe, Public Affairs Committee, United European Gastroenterology Federation 2003
Associate Editor United European Gastroenterology Journal. November
Chairperson Irish Helicobacter pylori Working Group 2016
European Society of Gastrointestinal Endoscopy Small Bowel Research Committee 2016
European Society of Gastrointestinal Endoscopy Small Bowel Quality Improvement Committee 2014
Irish Society of Gastroenterology Board November 2016
Member United European Gastroenterology Federation Meeting of Members (Council) 2015
Member National Societies Forum, United European Gastroenterology Federation 2015
Board Member Irish Society of Gastroenterology 2014
Details Date From Date To
European Society of Gastrointestinal Endoscopy (ESGE) Small Bowel Research Committee 2017
Member Eureka Panel, Eurostars Technical Expert 2015
Board Member Irish Society of Gastroenterology 2014
Member European Society of Gastrointestinal Endoscopy (ESGE) Small Bowel Quality Improvement Committee 2014
Director Trinity Academic Gastroenterology Group (TAGG) Research Centre 2012
Representative Irish Society of Gastroenterology National Clostridium Difficile Guidelines Subgroup Health Protection Surveillance Centre 2012 2013
Member Joint Adelaide and Meath and St James's Hospitals Research Ethics Committee 2012 2015
Member European Crohn's and Colitis Organisation (ECCO) 2011
Fellow Royal College of Physicians of Ireland 2010
Fellow Royal College Physicians of Edinburgh 2007
University of Dundee, Endoscopy Training Faculty Member 2008 2012
Epi-IBD European Crohn's and Colitis Organisation (ECCO) Research Consortium 2017
Grampian Lead Clinician, NHS Scotland Diagnostics Collaborative Programme 2006 2008
Member United European Gastroenterology Federation Trainee Mentor Faculty 2015
Chairperson Irish Helicobacter pylori Working Group 2016
Member United European Gastroenterology Federation Trainee Mentorship Faculty 2016
I-CARE (IBD Cancer and Serious Infections in Europe) Research Consortium 2016
Honorary Treasurer Medical Board, Adelaide and Meath Hospital 2016 2018
Member United European Gastroenterology Federation (UEGF) Council 2015
Member INITIative IBD Research Network 2015
National Representative United European Gastroenterology Federation (UEGF) National Societies Forum 2015
Spada C, McNamara D, Despott EJ, Adler S, Cash BD, Fernández-Urién I, Ivekovic H, Keuchel M, McAlindon M, Saurin JC, Panter S, Bellisario C, Minozzi S, Senore C, Bennett C, Bretthauer M, Dinis-Ribeiro M, Domagk D, Hassan C, Kaminski MF, Rees CJ, Valori R, Bisschops R, Rutter MD., Performance measures for small-bowel endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative., Endoscopy, 51, 2019, p574 - 598, Journal Article, PUBLISHED  TARA - Full Text  DOI
Holleran G, Hussey M, Smith S, McNamara D, Assessment of serum angiogenic factors as a diagnostic aid for small bowel angiodysplasia in patients with obscure gastrointestinal bleeding and anaemia, World Journal of Gastrointestinal Pathophysiology, 8, (3), 2017, p127 - 132, Journal Article, PUBLISHED  DOI
Tighe D, Hall B, Jeyarajah SK, Smith S, Breslin N, Ryan B, McNamara D., One-Year Clinical Outcomes in an IBD Cohort Who Have Previously Had Anti-TNFa Trough and Antibody Levels Assessed, Inflammatory Bowel Disease, 23, (7), 2017, p1154 - 1159, Journal Article, PUBLISHED  DOI
Yang S, Wang B, Humphries F, Jackson R, Healy M, Bergin R, Aviello G, Hall B, McNamara D, Walsh P, Russell S, Hussey S, O'Sullivan M, Darby T, Quinlan A, Shanahan F, Melgar S,Fallon PG, Moynagh P, Pellino3 ubiquitinates RIP2 and mediates NOD2-induced signaling and protective effects in colitis, Nature Immunology, 14, (9), 2013, p927 - 936, Journal Article, PUBLISHED  TARA - Full Text  DOI
McNamara D, El-Omar EM, How accurate are fecal tests for determination of cure after Helicobacter pylori eradication therapy?, Nature Clinical Practice. Gastroenterology & Hepatology, 4, (5), 2007, p248-9 , Journal Article, PUBLISHED  DOI
Holleran G, Barry S, Thornton O, Dobson M, McNamara D., The use of small bowel capsule endoscopy in iron deficiency anaemia: low impact on outcome in the medium term despite high diagnostic yield., European Journal of Gastroenterology and Hepatology, 25, (3), 2013, p327 - 332, Journal Article, PUBLISHED  DOI
Holleran G, Hussey M, Hall B, Dobson M, Thornton O, McNamara D., Small bowel angiodysplasia and novel disease associations: a cohort study., Scandinavian Journal of Gastroenterology, 48, (4), 2013, p433 - 438, Journal Article, PUBLISHED  DOI
Alakkari A, Gammell Y, O'Connor H, McNamara D, Breslin N,Ryan B, Audit of the appropriateness of hepatoma surveillance in a cohort of patients attending a dedicated haemachromatosis clinic., GUT, British and Irish Gastroenterology Meeting, April 2013, 62, 2013, ppA67-, Meeting Abstract, PUBLISHED  DOI
Lee CS, Leen R, O'Morain C, McNamara D, Screening for colorectal cancer: What fits best ?, Expert Reviews Gastroenterology Hepatology, 6, (3), 2012, p301 - 312, Review Article, PUBLISHED
Macdonald J, Porter V, McNamara D, Negative capsule endoscopy in patients with obscure GI bleeding predicts low rebleeding rates., Gastrointestinal Endoscopy, 68, (6), 2008, p1122-7 , Journal Article, PUBLISHED  DOI
  

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O'Connor C., McNamara D., Nakagome S., A statistical modelling reveals bi-directional chromatin scanning by RAG in the human TCR-alpha locus, bioRxiv, 2020, p14 , Journal Article, PUBLISHED

  

Award Date
United European Gastroenterology Federation, National Scholar Award. Colon capsule endoscopy (CCE) is an effective filter test for colonic polyp surveillance. July 2020
Irish Society of Gastroenterology Winter 2018 Video Presentation Prize. Balloon sphincteroplasty is a safe and reliable method to achieve biliary clearance in an at risk choledocholithiasis cohort. November 2018
Irish Society of Gastroenterology Winter 2018 Presentation Prize. Complementary and alternative therapies for inflammatory bowel disease. November 2018
National Scholar Award, United European Gastroenterology Federation, Impact of a novel educational tool on sun protection behaviour in an Irish IBD cohort. August 2018
O'Morain Research Award; Skin Cancer in at risk Irish Inflammatory Bowel Disease patients. June 2018
Presentation Prize Irish Society of Gastroenterology: ''Risk of Skin Cancer in IBD'' November 2017
National Scholar Award, United European Gastroenterology Federation, Feasibility of same day Colon capsule endoscopy (CCE) in patients with incomplete colonoscopy. October 2017
British & Irish Society of Gastroenterology (BIG) Presentation Prize. Correlation of relationship between infliximab and adalimumab trough and antibody levels with clinical response rates at completion of induction therapy April 2017
Irish Society of Gastroenterology Presentation Prize (Winter Meeting). Feasibility of same day Colon capsule endoscopy (CCE) in patients with incomplete colonoscopy. November 2016
Irish Society of Gastroenterology Presentation Prize (Winter Meeting). Adherence to European Society of Gastroenterology Endoscopy (ESGE) Polypectomy Guidelines: Retrospective experience from a tertiary Irish hospital. November 2016
National Scholar Award, United European Gastroenterology Federation. Anti-TNFá antibody induced psoriasis in patients with inflammatory bowel disease; a prospective Irish cohort study. October 2016
Irish Society of Gastroenterology Winter 2019 Oral Presentation Prize: Colon capsule endoscopy is an effective filter test for colonic polyp surveillance. November 2019
Best Paper Award, United European Gastroenterology. Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn's disease: Results from a randomised double-blind placebo-controlled study. United European Gastroenterology Journal 2015;3(3):294-302. October 2016
Meath Foundation Research Prize: O'Morain Medal. Title: Altered Glucocorticoid metabolism is associated with Inflammatory Bowel Disease . June 2016
Irish Society of Gastroenterology Presentation Prize (Summer Meeting). Can bacterial virulence factors predict antibiotic resistant H. pylori infection? June 2016
Irish Society of Gastroenterology Presentation Prize (Summer Meeting). The Changing Face of Coeliac Disease Presentation; a 55 Five Year Perspective in Ireland. June 2016
Irish Society of Gastroenterology Presentation Prize (Summer Meeting). Pre-assessment of patients awaiting endoscopic procedures while on anti-coagulation therapy. June 2016
European Crohn's and Colitis Organisation Research Grant. Optimal use of immunomodulator and biologic therapy in IBD. February 2016
Irish Society of Gastroenterology Presentation Prize (Winter Meeting). Accuracy of the CLO test versus histology in the diagnosis of Helicobacter pylori infection in patients undergoing gastroscopy at Tallaght Hospital. November 2015
Health Research Board Knowledge Exchange and Dissemination Scheme Awards 2015
United European Gastroenterology Week. Travel Grant. Assessment of serum angiopoietin levels in small bowel disorders; are they predictive of angiodysplasia? October 2015
Meath Foundation Research Grant 2015. The role of tissue glucocorticoid metabolism in Inflammatory Bowel Disease: The ColoCort Study. June 2015
Irish Society of Gastroenterology Winter 2019 Video Presentation Prize. Peutz Jegher small bowel polypectomy November 2019
Irish Society of Gastroenterology Presentation Prize (Summer Meeting). Altered tissue glucocorticoid metabolism is associated with IBD. June 2015
Irish Society of Gastroenterology Abstract Commendations (Summer Meeting). 1.The use of capsule endoscopy in the investigation of iron deficiency anaemia; young versus old. June 2015
Health Research Board Summer Student Scholarship. Are new generation fluoroquinolones useful for the treatment of Helicobacter pylori infection? June 2015
Health Research Board NSAFP Research Award. The role of angiopoietins and their mediators in symptomatic gastrointestinal angiodysplasia; novel diagnostic and therapeutic targets in chronic anaemia and obscure gastrointestinal bleeding. July 2015
Distinction Presentation Award, American Gastroenterological Association. The natural history of small bowel angiodysplasia May 2015
Given Imaging Research Award. Same day PillCam Colonoscopy following incomplete colonoscopy in an unselected clinical cohort Febuary 2015
HRB- SpR Academic Fellowship Award November 2014
Irish Society of Gastroenterology Presentation Prize (Winter Meeting). Longitudinal Irish angiodysplasia cohort study. November 2014
Health Research Board Research Award: An antimicrobial susceptibility testing-based approach for Helicobacter pylori eradication: will tailored therapy overcome the increasing failure of standard empirical therapy? HRA-POR-14-526 November 2014
22nd United European Gastroenterology Week. Presentation Prize. Gene expression levels of angiogenic factors in small bowel angiodysplasias. October 2014
Irish Society of Gastroenterology Winter 2019 Poster Presentation Prize: The safety and efficacy of ERM for large and intermediate rectal polyps. November 2019
Meath Foundation Research Prize: O'Morain Medal: A prospective 12 week mucosal healing assessment of small bowel Crohn's disease as detected by capsule endoscopy. June 2014
Irish Society of Gastroenterology Presentation Prize (Summer Meeting): Evaluation of a molecular genetics-based approach for the detection of Helicobacter pylori and antibiotic resistance. June 2014
Irish Society of Gastroenterology Presentation Prize (Winter Meeting): Small Bowel Crohn's Disease as detected by capsule endoscopy as a predictor of response to biologic therapy- a 3 month mucosal healing assessment. November 2013
United European Gastroenterology Federation National Scholar Award & Travel Grant: Elevated Angiopoietin 2 levels in small bowel angiodysplasia; future biomarker or therapeutic target. October 2013
Meath Foundation Research Prize: O'Morain Medal. Clinical associations with symptomatic angiodysplasia; a cohort study June 2013
American Gastroenterological Association Presentation of Distinction-Vitamin D Supplementation Improves Muscle Strength, Fatigue and Quality of Life in Patients With Crohn's Disease in Remission: Results of a Randomized Double-Blind Placebo-Controlled Study. May 2013
Meath Foundation Research Award: Tailored versus empirical therapy for H.pylori infection. February 2013
European Society of Gastrointestinal Endoscopy Research Award-The role of Small Bowel Capsule Endoscopy in the early assessment of Crohn's recurrence post surgery. October 2012
United European Gastroenterology Federation National Scholar Award-Comparison of faecal M2-PK and FIT in a population based bowel screening cohort. October 2012
American Gastroenterological Association Presentation of Distinction-Reduction in sequential FIT positivity and cancer detection rates in the Tallaght-Trinity College Colorectal Cancer Screening Program over time: evidence of cancer prevention? May 2012
Irish Society of Gastroenterology Winter 2019 Poster of Distinction Award: Is it worth repeating capsule endoscopy in suspected small bowel bleeding. November 2019
Irish Society of Gastroenterology Winter Meeting Presentation Prize-Preliminary results of capsule colonoscopy as a filter test in an Irish FIT positive screening cohort. November 2011
Irish Society of Gastroenterology Presentation Prize (Summer Meeting)-FIT levels and the efficacy of colorectal cancer screening in Irelands first bowel screening programme. November 2010
United European Gastroenterology Federation Presentation Prize-The efficacy of various FIT cut-off points in a two-step bowel cancer screening programme. October 2011
Leading Article Science Direct Publishing Group-In cases of obscure gastrointestinal bleeding, negative capsule endoscopy predicts good long-term outcome. Gastrointestinal Endoscopy October 2008
Scottish Society of Gastroenterology Presentation Prize- Comparison of MRI enterocolysis and capsule endoscopy in patients with small bowel Crohn's disease. June 2008
Deutscher Akademischer Austausch Dienst Scholarship German Federal Ministry of Education and Research. August 2002
American Gastroenterological Association Presentation of Distinction-Increased serotinergic responsivity plays a key role in non-ulcer dyspepsia and is not related to Helicobacter pylori infection. May 2001
Irish Society of Gastroenterology Presentation Prize-Dyspepsia: An audit of hospital based practice. June 1999
United European Gastroenterology Federation National Scholar Award, Helicobacter pylori infection inhibits NOTCH signaling in gastric epithelial cells and the gastric mucosa. October 2019
United European Gastroenterology Federation, Poster Champion. Shared angiogenic drivers of intestinal vascular disorders. October 2019
Irish Society of Gastroenterology Summer Meeting 2019. Best Poster Priz: Should sessile serrated polyps have separate surveillance? June 2019
Meath Foundation Prize for 2nd Year Medical Students 2018 November 2018
Major Description: Translational Gastroenterology. Founder and Co-Director of the TAGG (Trinity Academic Gastroenterology Group) Research Centre Major Themes: a) Infection: Helicobacter pylori infection. Chairperson Irish Helicobacter pylori Working group. Clinical Lead Faecal Microbiota Transplants, AMNCH. b) Inflammation: Inflammatory bowel disease. Member of the Epi -IBD European Research Group, iCare Research Consortium and INITIative IBD Research Network. c) Angiogenesis: Angiodysplasia. Member ESGE Small Bowel Research Committee. Member of the SBCE research network. Active projects: Helicobacter pylori infection. 1. Prospective randomised controlled trial of tailored versus standard eradication therapy 2. Helicobacter pylori antibiotic resistance monitoring 3. Genetic non-invasive identification of H. pylori antibiotic resistance 4. Management guideline development 5. Targeting Notch signaling in gastrointestinal inflammation. Inflammatory Bowel Disease 1. EU validation of the Lemann MRI Index 2. Epi-IBD Inception cohort study 3. Impact assessment of therapeutic drug monitoring and tailored therapy 4. Development of non-invasive diagnostic markers of mucosal healing 5. Risk of non-Melanoma and melanoma skin cancer in IBD patients on immunomodulators and anti-TNF-a medications. Physician and patient awareness and intervention study. 6. Multicentre assessment of antibodies to Vedolizumab and trough levels on clinical efficacy 7. ColoCort Study. Role of HSD 1 & 2 in corticosteroid resistance in IBD Angiodysplasia 1. Longitudinal assessment of serum angiopoietins in a cohort of angiodysplasia patients 2. Identification of novel putative angiogenic factors in an Irish angiodysplasia cohort 3. Multicentre trial of Octreotide analogues in the management of symptomatic angiodysplasia I have a proven track record as a principal investigator and postgraduate research student supervisor. Since my appointment in 2010 I have attracted and funded 2 PhD, 7 MD and 2 MSc students to work on projects in my areas of interest. Our work has already received numerous accolades and resulted in significant publications, including 3 National Scholar Awards from the United European Gastroenterology Federation and 2 Distinction Awards from the American Gastroenterological Association.