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Dr. Rachel Mary Mc Loughlin

Professor in Immunology (Biochemistry)

 Staphylococcus aureus induced immunosuppressive memory: consequences for bug and for host
 Profiling immune signatures predictive of outcome in Staphylococcus aureus infection: Advancing next-generation vaccine design
 Investigating the link between IL8 haplotype and susceptibility to bacterial and viral infection in calves
 Characterisation of Staphylococcal protein A - Bcell interactions to facilitate its development as a vaccine antigen
 Characterisation of epithelial surface immunity to Staphylococcus aureus: Targeting IL-22

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Details Date From Date To
International Cytokine Society 2002 to date
British Society Immunology 2010 to date
American Association of Immunology 2005 2013
Infectious Diseases Society of America 2006-2009
American Association of Microbiology 2011 to date
O'Brien E.C, McLoughlin R.M, Considering the â€~Alternatives†for Next-Generation Anti-Staphylococcus aureus Vaccine Development, Trends in Molecular Medicine, 25, (3), 2019, p171 - 184, Journal Article, PUBLISHED  DOI  URL
Lacey K.A, Mulcahy M.E, Towell A.M, Geoghegan J.A, McLoughlin R.M, Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target, PLoS pathogens, 15, (4), 2019, pe1007713-, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Connolly R, Denton M.D, Humphreys H, McLoughlin R.M, Would hemodialysis patients benefit from a Staphylococcus aureus vaccine?, Kidney International, 95, (3), 2019, p518 - 525, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Clowry, J., Irvine, A.D., McLoughlin, R.M., Next-generation anti"Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p78-81 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Leech JM, Lacey KA, Mulcahy ME, Medina E, McLoughlin RM, IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections., 198, (6), 2017, p2352-2365 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Stojkovic B, Mullen M.P, Donofrio G, McLoughlin R.M, Meade K.G, Interleukin 8 haplotypes drive divergent responses in uterine endometrial cells and are associated with somatic cell score in Holstein-Friesian cattle, Veterinary Immunology and Immunopathology, 184, 2017, p18 - 28, Notes: [Export Date: 20 February 2017], Journal Article, PUBLISHED  DOI  URL
Zaslona Z, Case S, Early JO, Lalor SJ, McLoughlin RM, Curtis AM, O'Neill LA., The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma., American Journal of Physiology Lung Cellular and Molecular Physiology, 2017, pL855-L860 , Journal Article, PUBLISHED  DOI
Finlay, C.M. and Stefanska, A.M. and Coleman, M.M. and Jahns, H. and Cassidy, J.P. and McLoughlin, R.M. and Mills, K.H.G., Secreted products of Fasciola hepatica inhibit the induction of T cell responses that mediate allergy, Parasite Immunology, 39, (10), 2017, pe12460 -, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Rudkin, J.K. and McLoughlin, R.M. and Preston, A. and Massey, R.C., Bacterial toxins: Offensive, defensive, or something else altogether?, PLoS Pathogens, 13, (9), 2017, e1006452.-, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Lacey KA, Leech JM, Lalor SJ, McCormack N, Geoghegan JA, McLoughlin RM., The Staphylococcus aureus Cell Wall-Anchored Protein Clumping Factor A Is an Important T Cell Antigen., Infection and immunity, 85, (12), 2017, pe00549-17 -, Journal Article, PUBLISHED  TARA - Full Text  DOI

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Award Date
Elected to Fellowship Trinity College Dublin 2016