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Dr. Anne McGettrick-Dillon

Senior Research Fellow (Biochemistry)

Connolly DJ, O'Neill LA, McGettrick AF., The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling, Journal of Biological Chemistry, 288, (8), 2013, p5616 - 5623, Journal Article, PUBLISHED  URL
Tannahill, GM, Curtis, AM, Adamik, J, Palsson-McDermott, EM, McGettrick, AF, Goel, G, Frezza, C, Bernard, NJ, Kelly, B, Foley, NH, Zheng, L, Gardet, A, Tong, Z, Jany, SS, Corr, SC, Haneklaus, M, Caffrey, BE, Pierce, K, Walmsley, S, Beasley, FC, Cummins, E, Nizet, V, Whyte, M, Taylor, CT, Lin, H, Masters, SL, Gottlieb, E, Kelly, VP, Clish, C, Auron, PE, Xavier, RJ, O'Neill, LAJ, Succinate is an inflammatory signal that induces IL-1 beta through HIF-1 alpha, NATURE, 496, (7444), 2013, p238-+ , Journal Article, PUBLISHED  DOI
McGettrick, A.F., O'Neill, L.A.J., How metabolism generates signals during innate immunity and inflammation, Journal of Biological Chemistry, 288, (32), 2013, 22893-22898 , Journal Article, PUBLISHED  DOI
Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF, , The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation, Nature communications, 3, 2012, p7 - 10, Journal Article, PUBLISHED  URL
McGettrick AF, O'Neill LA, Localisation and trafficking of Toll-like receptors: an important mode of regulation. , Current Opinion in Immunology, 22, (1), 2010, p20-27 , Notes: [PMID: 20060278], Journal Article, PUBLISHED  DOI
Palsson-McDermott E, Doyle S, McGettrick A, Hardy M, Husebye H, Banahan K, Gong M, Golenbock , Espevik T and O'Neill LAJ, TAG: a GOLD domain-containing splice variant of TRAM that negatively regulates the MyD88-independent pathway in TLR4 signaling, Nature Immunology, 10, 2009, p579 - 586 , Journal Article, PUBLISHED  DOI
McGettrick AF, O'Neill LA., Toll-like receptors: key activatory of leucocytes and regulator of haematopoiesis, Br J Haematol., 139, (2), 2007, p185-93 , Notes: [PMID: 17897294], Journal Article, PUBLISHED  DOI  URL
Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT, The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction, Proceedings of the National Academy of Sciences , 103, (16), 2006, p6299 - 6304, Notes: [PMID: 16603631], Journal Article, PUBLISHED  TARA - Full Text  DOI
McGettrick, A, Brint EK, Palsson-McDermott, EM, Rowe, DC, Golenbock, DT, Gay NJ, Fitzgerald, KA and O'Neill LA, Trif-related adapter molecule is phosphorylated by protein kinase C epsilon during Toll-like receptor 4 signalling, Proceedings of the National Academy of Sciences , 103, (24), 2006, p9196 - 9201, Notes: [PMID: 16757566 ], Journal Article, PUBLISHED  TARA - Full Text  DOI
Hardy, M, McGettrick, A and O'Neill, LAJ , Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene., Biochemical Journal, 380, (1), 2004, p83 - 93, Notes: [PMID: 14960149], Journal Article, PUBLISHED  TARA - Full Text  DOI

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