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Dr. Tony Mc Elligott

Assistant Prof in Molecular Haematology (Haematology)
TRINITY CENTRE, S J H

Assistant Prof in Molecular Haematology (Molecular Medicine Ireland)

  Apoptosis   Biology and therapy of myeloma   Drug development and evaluation   Haemotology   Leukemias and lymphomas   Multiple Myeloma
Details Date From Date To
Irish Association for Cancer Research 1995
Haematology Association of Ireland 2001
American Association for Cancer Research 2004
European Association for Cancer Research 2006
McElligott, AM, Maginn, EN, Greene, LM, McGuckin, S, Hayat, A, Browne, PV, Butini, S, Campiani, G, Catherwood, MA, Vandenberghe, E, Williams, DC, Zisterer, DM, Lawler, M, The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia., Cancer Research, 69, (21), 2009, p8366 - 8375, Notes: [PMID 19479253], Journal Article, PUBLISHED  DOI
Cunningham, O, McElligott, AM, Carroll, AM, Breen, E, Reguenga, C, Oliveira, ME, Azevedo, JE, Porter, RK, Selective detection of UCP 3 expression in skeletal muscle: effect of thyroid status and temperature acclimation., Biochimica et biophysica acta, 1604, (3), 2003, Journal Article, PUBLISHED
Forde JC., Maginn EN., McNamara G., Martin LM., Campiani GC. , Williams DC, Zisterer D.M, McElligott AM., Lawler M, , Lynch TH, Hollywood D., Marignol L, Microtubule-Targeting-Compound PBOX-15 Radiosensitizes Cancer Cells In Vitro , Cancer Biology and Therapy, 11, (4), 2011, p6 - 13, Journal Article, PUBLISHED
Bright SA, McElligott AM, O'Connell JW, O'Connor L, Carroll P, Campiani G, Deininger MW, Conneally E, Lawler M, Williams DC, Zisterer DM., Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo., British Journal of Cancer, 102, (10), 2010, p1474 - 1482, Journal Article, PUBLISHED
Reid, HM, McElligott, AM, McGlynn, H, Phenotypic alterations in Caki-1 cells as a consequence of TIMP-1 overexpression., Cancer letters, 169, (2), 2001, Journal Article, PUBLISHED
Maginn EN, Browne PV, Hayden P, Vandenberghe E, McDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM., PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells., British Journal of Cancer, 104, (2), 2011, p281 - 289, Journal Article, PUBLISHED  DOI
Ghnewa YG, O'Reilly VP, Vandenberghe E, Browne PV, McElligott AM, Doherty DG, Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells, Clinical Immunology, 183, 2017, p91 - 98, Journal Article, PUBLISHED  URL
Lysaght J, Verma NK, Maginn EN, Ryan JM, Campiani G, Zisterer DM, Williams DC, Browne PV, Lawler MP, McElligott AM., The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells, International Journal of Oncology, 42, (1), 2013, p239 - 249, Journal Article, PUBLISHED  TARA - Full Text  DOI
S A Bright, A M McElligott, J W O'Connell, L O'Connor, P Carroll, G Campiani, M W Deininger, E Conneally, M Lawler, D C Williams, and D.M Zisterer, Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo , British Journal of Cancer, 102, 2010, p1474 - 1482, Journal Article, PUBLISHED  TARA - Full Text
Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gargliardi M, Mc Elligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM, The vascular targeting agent Combretastatin-A4 and a novel cis-restricted {beta}-lactam analogue CA-432 induce apoptosis in human chronic myeloid leukemia cells and in ex vivo patient samples including those displaying multidrug resistance., The Journal of Pharmacology and Experimental Therapeutics, 335, (2), 2010, p302 - 313, Notes: [PMID: 20699346], Journal Article, PUBLISHED  DOI
  

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Anthony Davies, Anthony McElligott, Graham Pidgeon, Anthony Ryan, Ruth Foley, Cancer Biology where do we go next?, European Pharmaceutical Review, (1), 2010, Journal Article, PUBLISHED