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Professor Martin Caffrey

Personal Chair (Biochemistry)

Personal Chair (School Office - Medicine)

Personal Chair (Clinical Medicine)


 Structure-Function Studies of Membrane Proteins Involved in Quorum Sensing and the Pathogenicity of Pseudomonas aeruginosa
 Membrane Proteins. Crystallogenesis and X-ray Structure
 Robotic Dispensing of Cubic Phase for Crystallizing Membrane Proteins
 The Structural Biology of Membrane Proteins
 Marie Curie. Intra European Fellowship.

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Caffrey, M., A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes, Acta Crystallographica Section F Structural Biology Communications, 71, 2015, p3 - 18, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Li, D. Pye, V.E. Caffrey, M., Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method, Acta Crystallographica Section D Biological Crystallography, 71, 2015, p104 - 122, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Huang C.-Y, Olieric V, Ma P, Panepucci E, Diederichs K, Wang M, Caffrey M, In meso in situ serial X-ray crystallography of soluble and membrane proteins, Acta Crystallographica Section D: Biological Crystallography, 71, 2015, p1238 - 1256, Notes: [Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota A.E, Surana P, Kottur J, Nair D.T, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang B.-C, Steinmetz M.O, Caffrey M, Wang M, Fast native-SAD phasing for routine macromolecular structure determination, Nature Methods, 12, (2), 2015, p131 - 133, Notes: [Cited By :6 Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Kang Y, Zhou X.E, Gao X, He Y, Liu W, Ishchenko A, Barty A, White T.A, Yefanov O, Han G.W, Xu Q, De Waal P.W, Ke J, Tan M.H.E, Zhang C, Moeller A, West G.M, Pascal B.D, Van Eps N, Caro L.N, Vishnivetskiy S.A, Lee R.J, Suino-Powell K.M, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams G.J, Messerschmidt M, Gati C, Zatsepin N.A, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad C.E, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter C.S, Carragher B, Caffrey M, Jiang H, Chapman H.N, Spence J.C.H, Fromme P, Weierstall U, Ernst O.P, Katritch V, Gurevich V.V, Griffin P.R, Hubbell W.L, Stevens R.C, Cherezov V, Melcher K, Xu H.E, Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser, Nature, 523, (7562), 2015, p561 - 567, Notes: [Cited By :1 Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Stansfeld P.J, Goose J.E, Caffrey M, Carpenter E.P, Parker J.L, Newstead S, Sansom M.S.P, MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes, Structure, 23, (7), 2015, p1350 - 1361, Notes: [Cited By :1 Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota A.E, Surana P, Kottur J, Nair D.T, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang B.-C, Steinmetz M.O, Caffrey M, Wang M, Erratum: Fast native-SAD phasing for routine macromolecular structure determination (Nature Methods (2015) 12 (131-133)), Nature Methods, 12, (7), 2015, p692-, Notes: [Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Fowler P.W, Orwick-Rydmark M, Radestock S, Solcan N, Dijkman P.M, Lyons J.A, Kwok J, Caffrey M, Watts A, Forrest L.R, Newstead S, Gating topology of the proton-coupled oligopeptide symporters, Structure, 23, (2), 2015, p290 - 301, Notes: [Cited By :1 Export Date: 19 August 2015], Journal Article, PUBLISHED  DOI  URL
Li, DF, Howe, N, Dukkipati, A, Shah, STA, Bax, BD, Edge, C, Bridges, A, Hardwicke, P, Singh, OMP, Giblin, G, Pautsch, A, Pfau, R, Schnapp, G, Wang, MT, Olieric, V, Caffrey, M, Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy, CRYSTAL GROWTH & DESIGN, 14, (4), 2014, p2034-2047 , Journal Article, PUBLISHED  DOI
Johner, N, Mondal, S, Morra, G, Caffrey, M, Weinstein, H, Khelashvili, G, Protein and Lipid Interactions Driving Molecular Mechanisms of in meso Crystallization, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, (8), 2014, p3271-3284 , Journal Article, PUBLISHED  DOI
  

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