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Professor Martin Caffrey

Personal Chair (Biochemistry)
BIOMEDICAL SCIENCES INSTITUTE

Personal Chair (School Office - Medicine)

Personal Chair (Clinical Medicine)


 Structure-Function Studies of Membrane Proteins Involved in Quorum Sensing and the Pathogenicity of Pseudomonas aeruginosa
 Membrane Proteins. Crystallogenesis and X-ray Structure
 Robotic Dispensing of Cubic Phase for Crystallizing Membrane Proteins
 The Structural Biology of Membrane Proteins
 Marie Curie. Intra European Fellowship.

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Caffrey, M., A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes, Acta Crystallographica Section F Structural Biology Communications, 71, 2015, p3 - 18, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Li, D. Pye, V.E. Caffrey, M., Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method, Acta Crystallographica Section D Biological Crystallography, 71, 2015, p104 - 122, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Li, DF, Howe, N, Dukkipati, A, Shah, STA, Bax, BD, Edge, C, Bridges, A, Hardwicke, P, Singh, OMP, Giblin, G, Pautsch, A, Pfau, R, Schnapp, G, Wang, MT, Olieric, V, Caffrey, M, Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy, CRYSTAL GROWTH & DESIGN, 14, (4), 2014, p2034-2047 , Journal Article, PUBLISHED  DOI
Johner, N, Mondal, S, Morra, G, Caffrey, M, Weinstein, H, Khelashvili, G, Protein and Lipid Interactions Driving Molecular Mechanisms of in meso Crystallization, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, (8), 2014, p3271-3284 , Journal Article, PUBLISHED  DOI
Weierstall, U., James, D., Wang, C., (...), Caffrey, M., Cherezov, V., Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography, Nature Communications, 5, 2014, p3309-, Journal Article, PUBLISHED  DOI
Takeda, H. Hattori, M. Nishizawa, T. Yamashita, K. Shah, S.T.A. Caffrey, M. Maturana, A.D. Ishitani, R. Nureki, O., Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE, Nature Communications, 5, 2014, p5374-, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Boland, C. Li, D. Shah, S.T.A. Haberstock, S. Dötsch, V. Bernhard, F. Caffrey, M., Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination, Cellular and molecular life sciences : CMLS71, 24, 2014, p4895-4910 , Journal Article, PUBLISHED  DOI  URL
Tan, J. Rouse, S.L. Li, D. Pye, V.E. Vogeley, L. Brinth, A.R. El Arnaout, T. Whitney, J.C. Howell, P.L. Sansom, M.S.P. Caffrey, M., A conformational landscape for alginate secretion across the outer membrane of Pseudomonas aeruginosa, Acta Crystallographica Section D Biological Crystallography, 70, (8), 2014, p2054 - 2068, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Lyons, J.A. Parker, J.L. Solcan, N. Brinth, A. Li, D. Shah, S.T. Caffrey, M. Newstead, S., Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters, EMBO Reports, 15, (8), 2014, p886 - 893, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Nji, E. Li, D. Doyle, D.A. Caffrey, M., Cloning, expression, purification, crystallization and preliminary X-ray diffraction of a lysine-specific permease from Pseudomonas aeruginosa, Acta Crystallographica Section F Structural Biology Communications, 70, 2014, p1362 - 1367, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
  

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