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Dr. Stephen Maher

Ussher Assistant Professor (Surgery)


  Angiogenesis   Apoptosis   Apoptosis, molecular control   Autoimmune and hypersensitivity diseases   Autoimmunity   Bioinformatics   Breast cancer   Cancer genetics and cell biology including metastasis   Cell cycle control   Cell Death   Cellular, molecular and developmental immunology   Chronic Disease   Chronic inflamation   Coagulation biochemistry and disorders   Cytokines, Nitric Oxide   Cytoskelton, cell division   DNA transcription and translation   Gene targeting in breast cancer   Gene therapy   Gene transcription in human cancer   General surgery, upper GI, colorectal and breast   Genetic/Molecular epidemiology   Genomics   Haemotology   Human genetics   Immune system   Immunoassays   Immunochemistry and immunogenetics   Immunological response to surgical trauma   Immunotherapies   Immunotherapies for Cancer   Inflammation and coagulation syndromes   Inflammatory bowel disease   Innate immunology   Intra and intercellular signalling   Leukemias and lymphomas   Leukocyte Biology   Mammilian and human genetics and genomics   Membrane and protein trafficking   Mucosal immunology   Oesophageal cancer   Oesophageal, gastric, intestinal and pancreatic diseases   Oncogenes, apoptosis and tumour development   Protein processing, stability and regulation   Protein sequence, function and expression   Quantitative and molecular genetics   Radiotherapy   Radiotherapy, Biological response modifiers and chemoprevention   Regulatory methods of gene expression   RNA processing, stability and degradation   Stem Cell biology and hematopoiesis   Therapeutic and Clinical oncology   Therapeutic radiography   Tumour immunology and immunotherapy   Vascular Biology, Thrombosis
 The role of microRNA and random mitochondrial DNA mutations in a novel clinically-relevant isogenic model of radioresistance in oesophageal adenocarcinoma
 Tissue and Serum microRNA signatures for predicting response to chemoradiotherapy for oesophageal adenocarcinoma
 The role of the chemokine CCL28 (MEC) in oesophageal adenocarcinoma progression: interaction between the immune system and the tumour

Details Date From Date To
Irish Association of Cancer Research (IACR) Feb 2008 Present
American Association of Cancer Research (AACR): Associate Member Dec 2007 Present
International Society for Interferon and Cytokine Research (ISICR) Sep 2004 Present
microRNA in Oncogenesis in, editor(s)Trygve Tollefsbol , Epigenetics in Human Disease, Elsevier, 2012, [Niamh Lynam-Lennon, Steven G. Gray, Stephen G. Maher], Book Chapter, ACCEPTED
Basic concepts of inflammation and its role in carcinogenesis in, editor(s)Janusz A. Jankowski , Inflammation and Gastrointestinal Carcinogenesis, Springer, 2011, pp1 - 34, [Stephen G. Maher, John V. Reynolds], Book Chapter, PUBLISHED
Gijsbert J. Hotte, Niamh Lynam-Lennon, John V. Reynolds, Stephen G. Maher, Radiation sensitivity of oesophageal adenocarcinoma: The contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance, Radiation Research, 2011, Journal Article, SUBMITTED
Stephen G. Maher, Dermot T. McDowell, Ben C. Collins, Cian Muldoon, William M. Gallagher, John V. Reynolds, Serum proteomic profiling reveals that pre-treatment complement protein levels are predictive of esophageal cancer patient response to neo-adjuvant chemoradiation, Annals of Surgery, 254, (5), 2011, Journal Article, IN_PRESS
Niamh Lynam-Lennon, John V. Reynolds, Laure Marignol, Orla M Sheils, Graham P. Pidgeon, Stephen G. Maher, microRNA-31 modulates tumor sensitivity to radiation in esophageal cancer through the regulation of DNA repair genes, Journal of Molecular Medicine, 2011, Journal Article, SUBMITTED
Maher SG, Reynolds JV, Basic concepts of inflammation and its role in carcinogenesis., Recent results in cancer research. Fortschritte der Krebsforschung. Progr├Ęs dans les recherches sur le cancer, 185, 2011, p1-34 , Journal Article, PUBLISHED  DOI
Miriam Byrne, John V. Reynolds, James S. O'Donnell, Mary Keogan, Barry White, Mary Byrne, Seamas Murphy, Stephen G. Maher, Graham P. Pidgeon, Activation of the procoagulant response following neoadjuvant chemotherapy and radiation therapy, and long-term activation following major cancer surgery., British Journal of Cancer, 102, (1), 2010, p73 - 79, Journal Article, PUBLISHED
Lynam-Lennon N, Reynolds JV, Pidgeon GP, Lysaght J, Marignol L, Maher SG, Alterations in DNA repair efficiency are involved in the radioresistance of esophageal adenocarcinoma., Radiation research, 174, (6), 2010, p703-11 , Journal Article, PUBLISHED  DOI
Byrne M, Reynolds JV, O'Donnell JS, Keogan M, White B, Byrne M, Murphy S, Maher SG, Pidgeon GP, Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery., British Journal of Cancer, 102, (1), 2010, p73-9 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Niamh Lynam-Lennon, Stephen G. Maher, John V. Reynolds, The Roles of microRNA in Cancer and Apoptosis, Biological Reviews, 84, (1), 2009, p55 - 71, Journal Article, PUBLISHED

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Award Date
Irish Cancer Society Research Fellowship 2010
Donald Weir Medal for Research 2008 Nov 2008
NCI Visting Fellowship 2004 Jul 2004
Irish Representative at 39th LIYSF 1997