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Professor Dermot Kelleher

Adjunct Professor (School Office - Medicine)

 

Adjunct Professor (Clinical Medicine)


  5-AMINOSALICYLIC ACID   6-MERCAPTOPURINE   ABSORPTION   ACCUMULATION   ACTIN   ACTIN CYTOSKELETON   ACTIVATION   ACUTE BILIARY PANCREATITIS   ADENOCARCINOMA   ADHERENCE   ADHESION   ADHESION MOLECULE   ADHESION MOLECULES   ADHESION RECEPTORS   ALLELES   ALPHA-SUBUNITS   ANTI-D   ANTIGEN RECEPTOR   ANTIGENS   ANTIRETROVIRAL THERAPY   APOPTOSIS   ARACHIDONIC ACID   ASSOCIATION   AUTOIMMUNE ENTEROPATHY   AUTOMATED NEEDLE   AUTONOMIC NEUROPATHY   AZATHIOPRINE   AZODISAL SODIUM   BETA   BILE-DUCT OBSTRUCTION   BINDING   BINDING-PROTEINS   BIOCHEMISTRY   BREATH TEST   BROMODEOXYURIDINE   CAMPYLOBACTER-PYLORI   CANCER   Cancer Detection   CARDIOVASCULAR RISK-FACTORS   CD44   CD8-ALPHA HOMODIMER   CELIAC-DISEASE   CELL LYMPHOMA   CELL-ACTIVITY   CELL-ADHESION   CELLS   Cellular and molecular mechanisms regulating and resisting apoptosis   CENTRAL-NERVOUS-SYSTEM   CHEMOKINES   CHILDHOOD CELIAC-DISEASE   CHOLANGIOGRAPHY   CHOLEDOCHOLITHIASIS   CLASS-II   CLINICAL-TRIALS   COLITIS   COLON CANCER   COLONIC CARCINOMA   COMBINATION   COMMON BILE-DUCT   COMPLICATIONS   CONCENTRATE   CONTROLLED TRIAL   CROHN'S DISEASE   CROHNS-DISEASE   CROSS-LINKING   CRYOGLOBULINAEMIA   CUTANEOUS LYMPHOMA   CYCLOSPORINE METABOLISM   CYCLOSPORINE-A   CYTOCHROME-P-450   CYTOKINE SECRETION   CYTOSKELETON   CYTOTOXIC T CELL   CYTO-TOXICITY   DEPENDENT CROHNS-DISEASE   DEPENDENT DIABETES-MELLITUS   DEPENDENT PHOSPHORYLATION   DEXAMETHASONE   DIFFERENTIAL EXPRESSION   DISEASE   DIVERSITY   DNA   DNA FRAGMENTATION   DOMAIN   DOUBLE POSITIVE LYMPHOCYTES   DOUBLE-BLIND   DRUG-RESISTANCE   DRUGS   E2/NS1 REGION   EMBRYO FIBROBLASTS   ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY   ENDOTHELIUM   ENHANCEMENT   ENTEROCYTE   ENTEROCYTES   ENVELOPE PROTEIN   EPITHELIAL CELL   EPITHELIAL-CELLS   EPITHELIUM   ESCHERICHIA-COLI   EVOLUTION   EXPANSIONS   EXPRESSION   EXTRAHEPATIC TISSUES   EXTRATHYMIC DIFFERENTIATION   FACTOR TNF   FACTOR-VIII   FIBROSIS   FLOW   FLOW CYTOMETRIC ANALYSIS   FOOD INTOLERANCE   FUNCTIONAL DYSPEPSIA   FUNCTION-ASSOCIATED ANTIGEN-1   GAMMA-DELTA   GASTRIC INTRAEPITHELIAL LYMPHOCYTE   GASTRODUODENAL INJURY   GASTROINTESTINAL TISSUES   GENE   GENETIC DRIFT   Genetics of inflammatory disease   GENOME   GLUTEN-FREE DIET   GLUTEN-SENSITIVE ENTEROPATHY   GUT   HAEMOPHILIA   HEALTHY-VOLUNTEERS   HELICOBACTER PYLORI   HEMATOPOIETIC-CELLS   HEMOPHILIC PATIENTS   HEPATITIS C   HEPATITIS C VIRUS   HLA-DQ   HUMAN COLORECTAL TUMORS   HUMAN MONONUCLEAR PHAGOCYTES   HUMAN PERIPHERAL LYMPHOCYTES   HUMAN-LIVER   HUMAN-MONOCYTES   HVR1   ICAM-1   IDENTIFICATION   IFN-GAMMA   IMMUNE SELECTION   INDIVIDUALS   INDOMETHACIN   INDUCED PANCREATITIS   INFLAMMATORY-BOWEL-DISEASE   INTEGRIN   INTERFERON-ALPHA-2B   INTERLEUKIN-2   INTERMEDIATE FILAMENT PROTEINS   INTERMEDIATE FILAMENTS   INTESTINAL INTRAEPITHELIAL LYMPHOCYTES   INTRAEPITHELIAL LYMPHOCYTES   INVOLVEMENT   ISOENZYME   LEUKEMIA-CELLS   LEUKOCYTE ADHESION   LEUKOTRIENE-B4   LIPOXYGENASE   LIVER BIOPSY   LOCALIZATION   LPS   LYMPHOCYTE   LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1   MACROPHAGES   MAGNETIC-RESONANCE CHOLANGIOPANCREATOGRAPHY   MALABSORPTION   MALIGNANT HISTIOCYTOSIS   MANAGEMENT   MECHANISMS   MESALAZINE   MICE   MICROALBUMINURIA   MICROTUBULE-ASSOCIATED PROTEIN-2   Molecular Immunology   MONOCLONAL-ANTIBODY   MONOCYTES   Mucosal Immunology   NECROSIS FACTOR-ALPHA   NEGATIVE DUODENAL-ULCER   NEPHROTIC SYNDROME   NF-KAPPA B   NF-KAPPA-B   NON-A   NON-B-HEPATITIS   NONSTEROIDAL ANTIINFLAMMATORY DRUGS   ODDI DYSFUNCTION   PATHOGENESIS   PATHWAYS   PEPTIC-ULCER DISEASE   PERIPHERAL-BLOOD LYMPHOCYTES   PHORBOL ESTER   PHORBOL MYRISTATE ACETATE   PHORBOL-MYRISTATE ACETATE   PHYLOGENETIC   PKC ISOTYPES   POLYMERASE CHAIN-REACTION   POLYPS   POSSIBLE REGULATORY SYSTEM   PROLIFERATIVE ACTIVITY   PROSTAGLANDIN-E2   PROTEIN   PROTEIN C   PROTEIN KINASE C   PURPURA FULMINANS   QUASISPECIES   RANDOMIZED TRIAL   RAPID UREASE TEST   RAT   RECEPTOR   RECEPTORS   RECOGNITION   RESPONSES   RIBAVIRIN   SENSITIVE ENTEROPATHY   SEPSIS   SIGNAL-TRANSDUCTION PATHWAYS   SMALL-BOWEL   SPHINCTEROTOMY   SPRUE   STENOSIS   STIMULATION   SUBUNIT   SULFASALAZINE   SUPPRESSION   T HELPER CELL   T-CELL ADHESION   T-CELL LYMPHOMAS   THERAPY   TNF-ALPHA   TRANSFERRIN RECEPTOR   TRANSPORT CONDITIONS   TUMOR NECROSIS FACTOR   ULCERATIVE JEJUNITIS   ULCERATIVE-COLITIS   Vaccinology   VARIABILITY   VARIANTS   VILLOUS ATROPHY   VIRUS-INFECTION   VON WILLEBRAND'S DISEASE
Coleman C, Quinn E.M, Ryan A.W, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin A.P, Morris D.W, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, Wijmenga C, Kelleher D, Ennis S, Anney R.J.L, McManus R, Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci, Molecular Psychiatry, 24, 2016, p291 - 297, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
M├íjer F, Sharma R, Mullins C, Keogh L, Phipps S, Duggan S, Kelleher D, Keely S, Long A, Radics G, Wang J, Gilmer JF, New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid., Bioorganic & medicinal chemistry, 22, (1), 2014, p256-68 , Journal Article, PUBLISHED  TARA - Full Text  DOI
L.E. Collins, M Lynch, I Marszalowska, M. Kristek, K. Rochfort, M. O'Connell, H.J. Windle, D. Kelleher, C.E. Loscher, Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages, Microbes and Infection, 2014, Notes: [PMID 24300042], Journal Article, PUBLISHED  TARA - Full Text  DOI
McCarthy, S.E., Gillis, J., Kramer, M., (...), McCombie, W.R., Corvin, A. , De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability, Molecular Psychiatry, 19, 2014, p652-658 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Grealy, R., White, M., Stordeur, P., Kelleher, D., Doherty, D.G., McManus, R., Ryan, T., Characterising cytokine gene expression signatures in patients with severe sepsis, Mediators of Inflammation, 2013, 2013, part. no. 164246 , Notes: [ ], Journal Article, PUBLISHED  TARA - Full Text  DOI
Ruiz, JFM, Kedziora, K, Pigott, M, Keogh, B, Windle, H, Gavin, J, Kelleher, DP, Gilmer, JF, A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 23, (6), 2013, p1693-1698 , Journal Article, PUBLISHED  DOI
Queiroz, D.M.M., Harris, P.R., Sanderson, I.R., Windle, H.J., Walker, M.M., Rocha, A.M.C., Rocha, G.A., (...), Crabtree, J.E, Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study, PLoS ONE , 8, (7), 2013, art. no. e68833 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Verma, N.K., Conroy, J., Lyons, P.E., Coleman, J., O'Sullivan, M.P., Kornfeld, H., Kelleher, D., Volkov, Y., Autophagy induction by silver nanowires: A new aspect in the biocompatibility assessment of nanocomposite thin films, Toxicology and Applied Pharmacology, 164, (3), 2012, p451-461 , Notes: [ PubMed ID: 22959926], Journal Article, PUBLISHED  DOI
Gavin, J, Ruiz, JFM, Kedziora, K, Windle, H, Kelleher, DP, Gilmer, JF, Structure requirements for anaerobe processing of azo compounds: Implications for prodrug design, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7647-7652 , Journal Article, PUBLISHED  DOI
Ruiz, JFM, Kedziora, K, O'Reilly, M, Maguire, J, Keogh, B, Windle, H, Kelleher, DP, Gilmer, JF, Azo-reductase activated budesodine prodrugs for colon targeting, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7573-7577 , Journal Article, PUBLISHED  DOI
  

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Thomas Frodl, Yolande Ferguson, Andrew Fagan, Danusia Lisiecka, Angela Carballedo, Ian Daly, James Meaney & Dermot Kelleher, Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?, 2010, Working Paper, IN_PRESS

  

Award Date
WG Smith Prize in Pharmacology 1976
MB, BCh, BAO, BA (Hons) 1978
Arthur Ball Prize for Second Place in Surgery at Final MB Examination 1978
First Class Honours in Medicine at Final MB Examination 1978
Trinity College Travelling Scholarship in Medicine 1985
Wellcome Trust Senior Fellow in Clinical Science 1989
St Luke's Medal, Royal Academy of Medicine in Ireland 1993
Graves Medal, Royal Academy of Medicine 1994