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Professor John Kelly

Fellow Emeritus (Chemistry)
CHEMISTRY BUILDING

 jmkelly@tcd.ie

 3531896 1726


Biography

Brief Overview of Career 1965 B.Sc. (Chemistry), Manchester University, UK 1967 M.Sc., McMaster University, Canada (Supervisor J.J. McCullough) - 1970 Ph.D. University of London, UK (Supervisor George Porter) 1970-1971 Leverhulme Fellow at the University of West Indies 1971/3 Royal Society Fellow, Max Planck Institut für Kohlenforschung,Abteilung Photochemie, Mülheim. (Ernst Koerner von Gustorf) 1973 Lecturer in the Physical Chemistry, Trinity College Dublin 1987 Associate Professor in Chemistry, Trinity College Dublin 1989 - 1992 Director of Science of Materials, Trinity College Dublin 1993 - 2000 Head of Chemistry Department, Trinity College Dublin 2000 - 2001 Berkeley Fellow 2006 Professor in Chemistry - Member of the Royal Irish Academy - Fellow of the Royal Society of Chemistry Research Interests and Track Record Research interests cover areas of photochemistry, fast chemical reactions, and nucleic acids Current research projects falls into the following main areas (A) The transient spectroscopy of nucleic acids and photosensitisers. (B) The use of photochemical reagents to carry out site-specific reactions on DNA, in particular those involving photo-induced electron transfer. Previously also worked on nano-/micro-particles, especially (i) Silver nanoparticles of defined shape and size for biosensing, antibacterials and (ii) micro metal oxides and metal sulphides

Research Tags

  CHEMISTRY EXCITED-STATE   DNA BINDING MODES   FLASH-PHOTOLYSIS   FLUORESCENCE   LASER FLASH SPECTROSCOPY   MICRO PARTICLES   NANO PARTICLES   NANOCRYSTALS   NUCLEIC-ACIDS   PHOTO SENSITISATION   PHOTOCHEMISTRY   PHOTOCLEAVAGE OF DNA   PHOTOINDUCED ELECTRON-TRANSFER   POLYPYRIDYLRUTHENIUM (II) COMPLEXES   SILVER NANOPARTICLES   Ti02   TRANSIENT SPECTROSCOPY   Zn0

Representations

Details Date
Chairman of Royal Irish Academy Chemical and Physical Sciences Committee (2007-10) President of the Chemistry Division of the British Association for the Advancement of Science 2005. Founding vice-chairman of the Irish Research Scientists Association

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
Member of the Royal Irish Academy
Member of Royal Society of Chemistry
Frederico R. Baptista, Stephen J. Devereux, Sarah P. Gurung, James P. Hall, Igor V. Sazanovich, Michael Towrie, Christine J. Cardin, John A. Brazier, John M. Kelly, Susan J. Quinn, The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy, Chemical Communications, 2020, Journal Article, PUBLISHED
Sandra Estalayo-Adrián, Gavin J. McManus, Hannah L. Dalton, Aramballi J. Savyasachi, John M. Kelly, Thorfinnur Gunnlaugsson, Functionalisation of gold nanoparticles with ruthenium(ii) polypyridyl complexes for their application in cellular imaging, Dalton Transactions, 2020, Journal Article, PUBLISHED
Stephen J. Devereux, Fergus E. Poynton, Frederico R. Baptista, Thorfinnur Gunnlaugsson, Christine J. Cardin, Igor V. Sazanovich, Michael Towrie, John M. Kelly, Susan J. Quinn, Caught in the Loop: Binding of the [Ru(phen) 2 (dppz)] 2+ Light-Switch Compound to Quadruplex DNA in Solution Informed by Time-Resolved Infrared Spectroscopy, Chemistry - A European Journal, 26, 2020, p17103 - 17109, Journal Article, PUBLISHED
S. C. Padmanabhan, T.W. Collins, S.C. Pillai, D.E. McCormack, J. M. Kelly, J. D. Holmes and M. A. Morris, A conceptual change in crystallisation mechanisms of oxide materials from solutions in closed systems, Scientific Reports, 10, 2020, p18414-, Journal Article, PUBLISHED  TARA - Full Text  DOI
P. M. Keane, K. O'Sullivan, F. E. Poynton, B. C. Poulsen, I. V. Sazanovich, M. Towrie, C. J. Cardin, X.-Z.Sun, M. W. George, T. Gunnlaugsson, S. J. Quinn and J. M. Kelly, Understanding the factors controlling the photooxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides, Chemical Science, 11, 2020, p8600 - 8609, Journal Article, PUBLISHED  TARA - Full Text  DOI
S. Estalayo-Adrian, S. Blasco, S. A. Bright, G. J. McManus, G. Orellana, D. C. Williams, J. M. Kelly and T. Gunnlaugsson,, Water-soluble amphiphilic ruthenium(II) polypyridyl complexes as potential light-activated therapeutic agents, Chemical Communications, 56, 2020, p9332 - 9335, Journal Article, PUBLISHED  DOI
Keane, P.M. and Tory, J. and Towrie, M. and Sazanovich, I.V. and Cardin, C.J. and Quinn, S.J. and Hartl, F. and Kelly, J.M. and Long, C., Spectro-electrochemical Studies on [Ru(TAP)2(dppz)]2+ - Insights into the Mechanism of its Photosensitized Oxidation of Oligonucleotides, Inorganic Chemistry, 58, (1), 2019, p663-671 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Keane, P.M. and Kelly, J.M., Transient absorption and time-resolved vibrational studies of photophysical and photochemical processes in DNA-intercalating polypyridyl metal complexes or cationic porphyrins, Coordination Chemistry Reviews, 364, 2018, p137-154 , Notes: [cited By 2], Journal Article, PUBLISHED  DOI
Poynton, F.E. and Bright, S.A. and Blasco, S. and Williams, D.C. and Kelly, J.M. and Gunnlaugsson, T., The development of ruthenium(II) polypyridyl complexes and conjugates for: In vitro cellular and in vivo applications, Chemical Society Reviews, 46, (24), 2017, p7706-7756 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Keane P.M, Hall J.P, Poynton F.E, Poulsen B.C, Gurung S.P, Clark I.P, Sazanovich I.V, Towrie M, Gunnlaugsson T, Quinn S.J, Cardin C.J, Kelly J.M, Inosine Can Increase DNA's Susceptibility to Photo-oxidation by a RuII Complex due to Structural Change in the Minor Groove, Chemistry - A European Journal, 23, (43), 2017, p10344-10351 , Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
  

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M. Wojdyla, S. Gallagher, Y.K. Gun'ko, J. M. Kelly, S. J. Quinn, I.P. Clark, G.M. Greetham, M. Towrie and A.W. Parker, Ultrafast Transient Absorption Studies on CdTe and Chiral CdSe Quantum Dots - Central Laser Facility, Annual Report 2008-2009, Science and Technology Facilities Council, Rutherford Appleton Laboratory, 2009, 193-196, Report, PUBLISHED
P.M. Keane, M. Wojdyla, G.W. Doorley, J. M. Kelly, S. J. Quinn, I.P. Clark, G.M. Greetham, M. Towrie and A.W. Parker, Unravelling the Photodynamics of Cytosine-Rich Systems using Ultrafast Transient Infrared Spectroscopy - Central Laser Facility, Annual Report 2008-2009, Science and Technology Facilities Council,, Rutherford Appleton Laboratory, 2009, 183-186, Report, PUBLISHED
G.W. Doorley, J.M. Kelly, D.A. McGovern, S. Quinn, A.M. Whelan, K.L. Ronayne, Picosecond Processes in DNA monitored by transient infra-red absorption spectroscopy, Central Laser Facility, Annual Report 2005-2006, CCLRC Rutherford Appleton Laboratory, 2006, 129, 132, Report, PUBLISHED
J.M. Kelly, C.M. Creely, M.M. Feeney, S. Hudson, W.J. Blau, B. Elias, A. Kirsch- De Mesmaeker, P. Matousek, M. Towrie, A. W. Parker, Picosecond Studies of Ruthenium and Rhenium dipyridophenazine complexes in solution and when bound to polynucleotides, Central Laser Facility, Annual Report 2001-2002, CCLRC Rutherford Appleton Laboratory, 2002, 111 , 114, Report, PUBLISHED
J.M. Kelly, D.H. Grayson, D.C. Pepper, J.G. Vos, A. Yague-Ferrer, J.M. Clear, A. McCague, E.M. Moran, C.M. O'Connell, and M.M. O'Kane, Polymer-bound porphyrins and polymer-bound coordination compounds as converters of solar energy into chemical fuels , Munchen, EEC Solar Energy Project D, Contractors' meeting, EUR 7199 EN, 1980, Report, PUBLISHED

  

Awards and Honours

Award Date
Fellow of the Royal Society of Chemistry
Berkeley Fellow 2000 - 2001
Leverhulme Fellow at the University of West Indies 1970/1
Rita and John Cornforth Award (Royal Society of Chemistry) 2016
Boyle-Higgins Medal of the Institute of Chemistry of Ireland 2018

Research Interests

Description Of Research Interests

Research interests cover areas of photochemistry, fast chemical reactions, and nucleic acids Current research projects falls intothe following main areas (A) The transient spectroscopy of nucleic acids and photosensitisers. (B) The use of photochemical reagents to carry out site-specific reactions on DNA, in particular those involving photo-induced electron transfer. Previously also worked on nano-/micro-particles, especially (i) Silver nanoparticles of defined shape and size for biosensing, antibacterials and (ii) micro metal oxides and metal sulphides