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Professor Orla Hardiman

Professor of Neurology/Head of Academic (Clinical Medicine)


Professor of Neurology/Head of Academic (Trinity Inst. of Neurosciences (TCIN))

 Deep Phenotyping & Complex Genetics of ALS: A Multidisciplinary Population Based Approach
 Living and Dying with Amyotrophic Lateral Sclerosis: A Population based Analysis of Palliative Needs, Services and Outcomes in Non-malignant Terminal Illness

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Irish Fluent Fluent Fluent
Spanish Medium Medium Medium
Details Date From Date To
Member Royal Irish Academy 2015 present
Fellow, Trinity College Dublin 2015 present
Fellow of the Royal College of Physicians in Ireland 2001
Fellow of the American Academy of Neurology
Fellow of the American Neurological Association 2014
Bede P, Omer T, Finegan E, Chipika RH, Iyer PM, Doherty MA, Vajda A, Pender N, McLaughlin RL, Hutchinson S, Hardiman O., Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study., Brain Imaging Behav, 2018, p1 - 19, Notes: [ doi: 10.1007/s11682-018-9837-9. [Epub ahead of print] PMID:29423814 ], Journal Article, PUBLISHED
Andrews, J.A. and Cudkowicz, M.E. and Hardiman, O. and Meng, L. and Bian, A. and Lee, J. and Wolff, A.A. and Malik, F.I. and Shefner, J.M., VITALITY-ALS, a phase III trial of tirasemtiv, a selective fast skeletal muscle troponin activator, as a potential treatment for patients with amyotrophic lateral sclerosis: study design and baseline characteristics, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2018, p259-266 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Byrne RP, Martiniano R, Cassidy LM, Carrigan M, Hellenthal G, Hardiman O, Bradley DG, McLaughlin RL, Insular Celtic population structure and genomic footprints of migration, PLOS Genetics, 14, 2018, pe1007152 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Dukic S., Iyer P. M., Mohr K., Hardiman O., Lalor E. C., Nasseroleslami B., Estimation of coherence using the median is robust against EEG artefacts , 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) , Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) , Jeju, South Korea, 2017, 2017, pp3949 - 3952 , Conference Paper, PUBLISHED  DOI
Prieto-Fernández E, Díaz-de Usera A, Baeta M, Núñez C, Chbel F, Nadifi S, Rouault K, Férec C, Hardiman O, Pinheiro F, de Pancorbo M.M, A genetic overview of Atlantic coastal populations from Europe and North-West Africa based on a 17 X-STR panel, Forensic Science International: Genetics, 27, 2017, p167 - 171, Notes: [Export Date: 16 February 2017], Journal Article, PUBLISHED  DOI  URL
Lefter S, Hardiman O, Ryan A.M, A population-based epidemiologic study of adult neuromuscular disease in the Republic of Ireland, Neurology, 88, (3), 2017, p304 - 313, Notes: [Export Date: 16 February 2017], Journal Article, PUBLISHED  DOI  URL
Rooney J, Fogh I, Westeneng HJ, Vajda A, McLaughlin R, Heverin M, Jones A, van Eijk R, Calvo A, Mazzini L, Shaw C, Morrison K, Shaw PJ, Robberecht W, Van Damme P, Al-Chalabi A, van den Berg L, Chiò A, Veldink J, Hardiman O, C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis., Journal of neurology, neurosurgery, and psychiatry, 88, (4), 2017, p281 - 281, Journal Article, PUBLISHED  DOI
Burke T, Lonergan K, Pinto-Grau M, Elamin M, Bede P, Madden C, Hardiman O & Pender N., Visual Encoding, Consolidation, and Retrieval in Amyotrophic Lateral Sclerosis: Executive Function as a Mediator, and Predictor of Performance., Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2017, p1-9 , Journal Article, PUBLISHED  DOI
Van Der Spek RA, Van Rheenen W, Pulit SL, Kenna KP, Ticozzi N, Kooyman M, McLaughlin RL, Moisse M, Van Eijk KR, Van Vugt JJFA, Andersen P, Nazli Basak A, Blair I, De Carvalho M, Chio A, Corcia P, Couratier P, Drory VE, Glass JD, Hardiman O, Mora JS, Morrison KE, Mitne-Neto M, Robberecht W, Shaw PJ, Panadés MP, Van Damme P, Silani V, Gotkine M, Weber M, Van Es MA, Landers JE, Al-Chalabi A, Van Den Berg LH, Veldink JH; PROJECT MINE ALS SEQUENCING CONSORTIUM., Reconsidering the causality of TIA1 mutations in ALS, Amyotroph Lateral Scler Frontotemporal Degener, 13, 2017, p1-3 , Journal Article, PUBLISHED
Bede P, Hardiman O. , Longitudinal structural changes in ALS: a three time-point imaging study of white and gray matter degeneration. , . Amyotroph Lateral Scler Frontotemporal Degener, 2017, p1 - 10, Notes: [2017 Dec 7:1-10. doi: 10.1080/21678421.2017.1407795. [Epub ahead of print] PMID:29214883 ], Journal Article, PUBLISHED

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Peschansky, V., Bedlack, R., Quinn, C., (...), Weber, C., Denson, K.H., ALSUntangled 38: L-serine, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18, (1-2), 2017, p148-151 , Notes: [ ], Journal Article, PUBLISHED


Award Date
International Alliance of ALS/MND Forbes Norris Award 2011
Sheila Essey Award, American Academy of Neuroloy 2009
American Academy of Neurology Palatucci Advocacy Award
Elected Member, Royal Irish Academy 2015
Epidemiology, genetics and deep phenotyping of Amyotrophic Lateral Sclerosis: Health Services Research; Drug development and Clinical Trials