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Dr. Emma Creagh

Assistant Professor (Biochemistry)

Ofijalska, K. and Creagh, E.M., Role of caspase-11 in a DSS-colitis model of IBD, The innate immune response in the pathogenesis of infectious disease, Minas Gerais, Brazil, 10-15 May 2013, 2013, Poster, PRESENTED
Oficjalska, K., Laukens, D. and Creagh, E.M., Investigation of the role of caspases in a DSS-colitis model of IBD, Irish Society of Gastroenterology Winter Meeting, Dublin, Ireland, 23rd-24th Nov. 2012, 2012, Oral Presentation, PRESENTED
Harris, J..Hartman, M., Roche, C., Zeng, S.G., O'Shea, A., Sharp, F.A., Lambe, E.M., Creagh, E.M., Golenbock, D.T., Tschopp, J., Kornfeld, H., Fitzgerald, K.A. and Lavelle, E.C , Autophagy controls IL-1ß secretion by targeting pro-IL-1ß for degradation, The Journal of Biological Chemistry, 286, 2011, p9587 - 9597, Journal Article, PUBLISHED  TARA - Full Text
Lavelle EC, Murphy C, O'Neill LA, Creagh EM, The role of TLRs, NLRs and RLRs in mucosal innate immunity and homeostasis , Mucosal Immunology, 3, (1), 2010, p17 - 28, Notes: [PMID: 19890268], Journal Article, PUBLISHED
Becker CE, Creagh EM, O'Neill LA, Rab39a binds caspase-1 and is required for caspase-1-dependent il-1{beta} secretion, Journal of Biological Chemistry, 284, (50), 2009, p34531-34537 , Notes: [PMID: 19833722], Journal Article, PUBLISHED  TARA - Full Text  DOI
Sharp, F., Ruane, D., Claas, B., Creagh, E., Harris, J., Malyala, P., Singh, M., O'Hagan, D.T., Pétrilli, V., Tschopp, J., O'Neill, L.A.J. and *Lavelle, E.C, Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome., Proceedings of the National Academy of Sciences of the U.S.A, 106, (3), 2009, p870-875 , Notes: [PMID: 19139407], Journal Article, PUBLISHED  TARA - Full Text  DOI
Creagh EM, Brumatti G, Sheridan C, Duriez PJ, Taylor RC, Cullen SP, Adrain C, Martin SJ, Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival., PloS one, 4, (3), 2009, pe5055 , Journal Article, PUBLISHED  TARA - Full Text
Creagh E and O'Neill LAJ, TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity, Trends Immunol., 27, (8), 2006, p352 - 357, Notes: [PMID: 16807108], Journal Article, PUBLISHED  DOI  URL
Adrain C, Creagh EM, Cullen SP, Martin SJ, Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man, JOURNAL OF BIOLOGICAL CHEMISTRY, 279, (35), 2004, p36923 - 36930, Notes: [PMID: 15210720 ], Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Murphy BM, Creagh EM, Martin SJ, Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation, JOURNAL OF BIOLOGICAL CHEMISTRY, 279, (35), 2004, p36916 - 36922, Journal Article, PUBLISHED  TARA - Full Text

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Caspase detection and analysis in, editor(s)Edited by D. Hughes and H. Mehmet , Cell Proliferation and Apoptosis , Oxford, UK, Bios Scientific Publishers, 2003, pp233 - 253, [Creagh, E. M., Adrain C., and S.J Martin], Book Chapter, PUBLISHED
Caspase cascades in apoptosis in, editor(s)M. Los and H. Walczak , In Caspases-Their role in Cell Death and Cell Survival, New York, USA, Landes Bioscience/Kluwer Academic/Plenum Publishers, 2002, pp41 - 51, [S.J Martin], Book Chapter, PUBLISHED