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Dr. Emma Creagh

Associate Professor (Biochemistry)

 ecreagh@tcd.ie

 3531896 2539


Research Tags

  CANCER   CANCER IMMUNOLOGY   CASPASES   Inflammasome-mediated inflammation   INFLAMMATION

Languages

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
Irish Association for Cancer Research (Senior Council Member since 2020) 2000 present
American Society for Immunology 2014 Present
International Society for Mucosal Immunology 2015 Present
Irish Society of Gastroenterology 2012 Present
Irish Society of Immunology 2010 Present
Irish Epithelial Physiology Group 2016 Present
Evaluating host responses to Helicobacter pylori using ELISA and Western Blot. in, Methods in Molecular Biology, Springer, 2021, pp175-190 , [C. Nulty, G. Barber, E. Flis, E.M. Creagh. ], Book Chapter, PUBLISHED  DOI
E. Flis, G. Barber, C. Nulty, B. Keogh, P. McGuirk, A. Anand, J. O'Sullivan, M. Quante, E.M. Creagh. , Identification of TLR2 signalling mechanisms which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression, Cancers (Basel) , 13, (9), 2021, p2065 - 2081, Journal Article, PUBLISHED  DOI
Agnew, A., Nulty, C., Creagh, E.M., Regulation, Activation and Function of Caspase-11 during Health and Disease., International Journal of Molecular Science, 22, (4), 2021, p1506-, Journal Article, PUBLISHED  DOI
Zaslona Z, Flis E, Nulty C, Kearney J, Fitzgerald R, Douglas AR, McNamara D, Smith S, O'Neill LAJ, Creagh EM., Caspase-4: A Therapeutic Target for Peptic Ulcer Disease, Immunohorizons, 4, (10), 2021, p627 - 633, Journal Article, PUBLISHED  DOI
Flis E. & Creagh E.M., HMGB1- mediates inflammatory TLR2 pathways during oesophageal adenocarcinoma, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020, Conference Paper, PRESENTED
Nulty C. & Creagh E.M., The Influence of Hormone Receptor Status on the Expression of Inflammatory Caspases in Tumour Microenvironment, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020, Conference Paper, PRESENTED
G. Barber, A. Anand, K. Oficjalska, J.J. Phelan, A. B. Heeran, E. Flis, N. E. Clarke, J. A. Watson, J. Strangmann, B. Flood, H. O'Neill, D. O'Toole, F. MacCarthy, N. Ravi, J. V. Reynolds, E.W. Kay, M. Quante, J. O'Sullivan, E.M. Creagh., Characterizing caspase-1 involvement during esophageal disease progression. , Cancer Immunology Immunotherapy, 69, (12), 2020, p2635 - 2649, Journal Article, PUBLISHED  TARA - Full Text  DOI
Z. Zas³ona , E. Flis, M.M. Wilk, R.G. Carroll, E.M. Palsson-McDermott, M.M. Hughes, C. Diskin, K. Banahan, D.G. Ryan, A. Hooftman, A. Misiak, J. Kearney, G. Lochnit, W. Bertrams, T. Greulich, B. Schmeck, O.J. McElvaney, K.H.G. Mills, E.C. Lavelle, M. Wygrecka, E.M. Creagh & L.A.J. O'Neill , Caspase-11 promotes allergic airway inflammation, Nature Communications, 2020, Notes: [10.1038/s41467-020-14945-2], Journal Article, PUBLISHED  TARA - Full Text  URL
Creagh, E.M., Kay, E.W., Flood, B., Oficjalska, K., Doherty, G. and Ryan, E., 'Method And Kit For Identification Of Inflamed And Malignant Intestinal Tissue', Trinity Technical Transfer Office, EP14182681.8 , 2020, Trinity College, Patent, GRANTED  Other
Creagh, E.M., Inflammatory caspases during colorectal cancer, Cancer Biology & Immunology World Congress, Milan, Italy, March 11-13th 2019, 2019, Conference Paper, PRESENTED  URL
  

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Creagh, E.M., Contribution of Inflammatory caspases to IBD & CRC, INITIative Network meeting, Dublin, Ireland, 23rd November 2018, 2018, Invited Talk, PRESENTED
Flis, E and Creagh, E.M., Role of TLR2 in Oesophageal Adenocarcinoma Progression, Training in Cancer Mechanisms & Therapeutics Meeting, Queens University, Belfast, 16th April 2018, 2018, Oral Presentation, PRESENTED
Caspase detection and analysis in, editor(s)Edited by D. Hughes and H. Mehmet , Cell Proliferation and Apoptosis , Oxford, UK, Bios Scientific Publishers, 2003, pp233 - 253, [Creagh, E. M., Adrain C., and S.J Martin], Book Chapter, PUBLISHED
Caspase cascades in apoptosis in, editor(s)M. Los and H. Walczak , In Caspases-Their role in Cell Death and Cell Survival, New York, USA, Landes Bioscience/Kluwer Academic/Plenum Publishers, 2002, pp41 - 51, [S.J Martin], Book Chapter, PUBLISHED

  

Awards and Honours

Award Date
Wellcome Trust Career Development Fellowship 2006-2011
Broad Medical Research Program Fellowship 2010-2012
TCD Pathfinder Award 2015
Winner - Oral presentation - Irish Society of Gastroenterology Meeting 2016
Voted 'Favorite Woman in Science' 2017, 2018 and 2019 by TCD General Science Students 2017-2019
Elected Senior Council Member - Irish Association for Cancer Research (IACR). 2020