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Professor Colm Bergin

CONSULTANT PHYSICIAN /Clinical ProfessOR (Clinical Medicine)

 


O'Connell S, Lillis D, Cotter A, O'Dea S, Tuite H, Fleming C, Crowley B, Fitzgerald I, Dalby L, Barry H, Shields D, Norris S, Plunkett PK, Bergin C., Opt-Out Panel Testing for HIV, Hepatitis B and Hepatitis C in an Urban Emergency Department: A Pilot Study, PLoS One, 11, (3), 2016, Notes: [OBJECTIVES: Studies suggest 2 per 1000 people in Dublin are living with HIV, the level above which universal screening is advised. We aimed to assess the feasibility and acceptability of a universal opt-out HIV, Hepatitis B and Hepatitis C testing programme for Emergency Department patients and to describe the incidence and prevalence of blood-borne viruses in this population. METHODS: An opt-out ED blood borne virus screening programme was piloted from March 2014 to January 2015. Patients undergoing blood sampling during routine clinical care were offered HIV 1&2 antibody/antigen assay, HBV surface antigen and HCV antibody tests. Linkage to care where necessary was co-ordinated by the study team. New diagnosis and prevalence rates were defined as the new cases per 1000 tested and number of positive tests per 1000 tested respectively. RESULTS: Over 45 weeks of testing, of 10,000 patient visits, 8,839 individual patient samples were available for analysis following removal of duplicates. A sustained target uptake of >50% was obtained after week 3. 97(1.09%), 44(0.49%) and 447(5.05%) HIV, Hepatitis B and Hepatitis C tests were positive respectively. Of these, 7(0.08%), 20(0.22%) and 58(0.66%) were new diagnoses of HIV, Hepatitis B and Hepatitis C respectively. The new diagnosis rate for HIV, Hepatitis B and Hepatitis C was 0.8, 2.26 and 6.5 per 1000 and study prevalence for HIV, Hepatitis B and Hepatitis C was 11.0, 5.0 and 50.5 per 1000 respectively. CONCLUSIONS: Opt-out blood borne viral screening was feasible and acceptable in an inner-city ED. Blood borne viral infections were prevalent in this population and newly diagnosed cases were diagnosed and linked to care. These results suggest widespread blood borne viral testing in differing clinical locations with differing population demographic risks may be warranted.], Journal Article, PUBLISHED  DOI
Kieran JA, Norris S, O'Leary A, Walsh C, Merriman R, Houlihan D, McCormick PA, McKiernan S, Bergin C, Barry M, Hepatitis C in the era of direct-acting antivirals: real-world costs of untreated chronic hepatitis C; a cross-sectional study., BMC infectious diseases, 15, 2015, p471 , Journal Article, PUBLISHED  TARA - Full Text  DOI
S O'Connell, Lillis D, O'Dea S, H Tuite, C Fleming, D Shields, S Norris, B Crowley. P Plunkett, C Bergin , Results of a Universal Testing Programme for Blood Borne Viruses in an Urban Emergency Department, including Rates of Diagnosis and Linkage to Care, AASLD The Liver Meeting, Boston, MA, November 7-11 2014, 2014, Meeting Abstract, PRESENTED  TARA - Full Text
Kieran J, Schmitz S, O'Leary A, Walsh C, Bergin C, Norris S, Barry M, The relative efficacy of boceprevir and telaprevir in the treatment of hepatitis C virus genotype 1., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56, (2), 2013, p228-35 , Journal Article, PUBLISHED
NĂ­ Cheallaigh C, Fitzgerald I, Grace J, Jagjit Singh G, El-Eraki N, Gibbons N, Keane J, Rogers TR, Clarke S, Bergin C, Interferon Gamma Release Assays for the Diagnosis of Latent TB Infection in HIV-Infected Individuals in a Low TB Burden Country., PloS one, 8, (1), 2013, pe53330 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Morley D, McNamara P, Kennelly S, McMahon G, Bergin C, Limitations to the identification of HIV-associated neurocognitive disorders in clinical practice., HIV medicine, 14, (8), 2013, p497-502 , Journal Article, PUBLISHED
Dillon AA, Farrell G, Hegarty JE, O'Grady JG, Norris S, Bergin C, The advent of successful organ transplantation in the Irish HIV positive cohort., Irish Journal of Medical Science, 181, (1), 2012, p49-52 , Journal Article, PUBLISHED
De Gascun CF, Waters A, Regan C, O'Halloran J, Farrell G, Coughlan S, Bergin C, Powderly WG, Hall WW, Documented prevalence of HIV type 1 antiretroviral transmitted drug resistance in Ireland from 2004 to 2008., AIDS Research and Human Retroviruses, 28, (3), 2012, p276-81 , Journal Article, PUBLISHED
Breslin TM, Ionmhain UN, Bergin C, Gallagher D, Collins N, Kinsella N, McMahon G, Malarial cases presenting to a European urban Emergency Department., European Journal of Emergency Medicine : official journal of the European Society for Emergency Medicine, 2012, Journal Article, IN_PRESS
De Gascun CF, Waters A, Regan CM, O'Halloran J, Farrell G, Coughlan S, Bergin C, Powderly WG, Hall WW, Human Immunodeficiency Virus Type 1 in Ireland: Phylogenetic Evidence for Risk Group-Specific Subepidemics., AIDS Research and Human Retroviruses, 2012, Journal Article, IN_PRESS
  

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