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Dr. Conor Buckley

Assistant Professor (Mechanical & Manuf. Eng)
PARSONS BUILDING


Buckley graduated with a degree in Mechanical Engineering (2001) and completed a PhD in the area of scaffolds and bone tissue engineering (2007). In 2011, he was appointed as Assistant Professor in Biomedical Engineering (Biomaterials and Tissue Engineering) at Trinity College Dublin. He is a Principal investigator (PI) in the Trinity Centre for Bioengineering and a funded Investigator (FI) in the Advanced Materials and Bioengineering Research (AMBER) Centre at Trinity College Dublin. His research focuses on developing novel biomaterials and cell based strategies for tissue regeneration using minimally invasive technologies (http://www.mee.tcd.ie/regenerative/People/CBuckley). He is also the Director of Orthobiologics and Adjunct Assistant Prof in the Academic unit of Orthopaedics and Sports Medicine and Course Director of the award winning MSc in Bioengineering. Buckley founded Med3DP (www.med3dp.com), an initiative to develop medical devices for humanitarian healthcare using 3D printing technology. Buckley is a co-founding member and treasurer of European Society- Educating Students in Engineering and Medicine (ESEM) and also serves as a board member for Common European Masters in Biomedical Engineering (CEMACUBE). In 2014 he was awarded an IRC New Foundations Scholarship and was a visiting Professor in the Department of Orthopaedics, at Mount Sinai, New York, USA. He has served as reviewer for 22 leading journals in the fields of Biomaterials and Tissue Engineering and is an editorial board member of Frontiers- Bioengineering and Biotechnology. He was a co-chair of the 19th Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Dublin, Ireland, Jan 2013 and has also served as an external grant reviewer for European agencies. He is also a scientific ambassador, education and outreach mentor for the Trinity Science Gallery which involves showcasing of research and mentoring secondary level students interested in pursuing a degree/career in engineering and science. Buckley has previously mentored 1 postdoctoral fellow (injectable biomaterials for minimally invasive repair of the intervertebral disc), supervised 4 PhD and 20 M.Sc. (Bioengineering). His current research group consists of 2 Postdoctoral Fellows, 3 Ph.D. and 2 MSc students in the area of Biomaterials & Tissue Engineering. Prof Buckley has been awarded a number of grants in the area of tissue engineering and regenerative medicine as Principal Investigator (>1.26million) and as co-investigator (>3.45million) and has published 60 international peer reviewed journal articles and over 150 conference publications (h index= 25, citations=1716, May 2017). Most recently he received a Career Development Award (Intraoperative Single Stage Procedure for Intervertebral Disc Regeneration (INSPIRE)) from Science Foundation Ireland.
  Biomaterials   Tissue Engineering
 A Bioactive Collagen-Based Conduit For Peripheral Nerve Repair
 Isolation and characterization of different mesenchymal stem cell populations
 Intraoperative Single Stage Procedure for Intervertebral Disc Regeneration (INSPIRE)
 Towards a Single Stage Procedure for Intervertebral Disc Repair using Nasal Derived Chondrocytes (NasDisc)
 Over-the-wire Drug Delivery Device

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Details Date
Quality and Qualifications Ireland (QQI) panel expert. QQI is the national agency responsible for the National Framework of Qualifications (NFQ). Dec 2016-Jan 2017
Visceral- Living Art Experiment, TCD Science Gallery, Ireland. Exhibiting demonstrating ten years of SymbioticA's challenging work at the frontier between fine art and biotechnology revolving around the nature of the living and non-living. Contribution: Chief Scientific Advisor. 28th Jan- 25th Feb 2011
Transformations, TCD Science Gallery, Ireland, HEA celebration of 10 years of PRTLI funding. Contribution: Co-organised the Exploring Bioengineering exhibit demonstrating the research undertaken by TCBE since its inception. 27th Nov- 2nd Dec 2008
Techno Threads- Victimless leather, TCD Science Gallery, Ireland. Contribution: Setup, installation and management of exhibition piece which demonstrated how tissue cultures could be used to create semi-living clothes 26th Apr- 25th Jul 2008
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Educating Students in Engineering and Medicine (ESEM), Co- Founding member and Treasurer 2015 Present
Tissue Engineering and Regenerative Medicine International Society (TERMIS) 2009 Present
European Society of Biomechanics (ESB) 2009 Present
Orthopaedic Research Society (ORS) 2009 Present
Vedicherla S.V. and Buckley C.T. , In Vitro Extracellular Matrix Accumulation of Nasal and Articular Chondrocytes for Intervertebral Disc Repair, Tissue and Cell , 2017, Notes: [https://doi.org/10.1016/j.tice.2017.05.002], Journal Article, ACCEPTED  TARA - Full Text
Srujana Vedicherla, Conor Timothy Buckley, Rapid Chondrocyte Isolation for Tissue Engineering Applications: The Effect of Enzyme Concentration and Temporal Exposure on the Matrix Forming Capacity of Nasal Derived Chondrocytes, BioMed Research International, 2017, 2017, p1--12 , Journal Article, PUBLISHED  TARA - Full Text
Almeida H.V., Sathy B.N., Dudurych I., Buckley C.T., O'Brien F.J. and Kelly D.J. , Shape-Memory Alginate Scaffolds Functionalized with either Type I or Type II Collagen for Cartilage Tissue Engineering, Tissue Engineering , 23, (1-2), 2017, p55 - 68, Journal Article, PUBLISHED
Gansau J. and Buckley C.T., Injectable cell-loaded microcapsules as a potential strategy for nucleus pulposus regeneration., BioSpine 2017- 6th International Congress on Biotechnologies for Spinal Surgery, Langenbeck-Virchow-Haus, Berlin, Germany, 2017, Poster, PRESENTED
Vedicherla S.V., Withers D., Moran C.J. and Buckley C.T. , Enhanced Integration using Freshly Isolated Human Infrapatellar Fat Pad Cell and Chondrocyte Coculture with a Polyurethane Meniscal Replacement, 63rd Annual Meeting of the Orthopaedic Research Society, San Diego Convention Center, California, USA, 2017, Poster, PRESENTED
Browe D., Mahon O., Dudurych I., Dunne A., Buckley C.T. and Kelly D.J., The Combination of Rapidly Isolated Infrapatellar Fat Pad Stromal Cells and Glyoxal Cross-linked Type II Collagen Scaffolds As a Single-stage Therapy For Articular Cartilage Repair, 63rd Annual Meeting of the Orthopaedic Research Society, San Diego Convention Center, California, USA, 2017, Poster, PRESENTED
Carroll S.F., Sathy B.N., Buckley C.T. and Kelly D.J. , Cyclic Tensile Strain Directs Both Intramembranous And Endochondral Ossification Of MSCs, 63rd Annual Meeting of the Orthopaedic Research Society, San Diego Convention Center, California, USA, 2017, Poster, PRESENTED
Vedicherla, S., Buckley, C.T., Cell-based therapies for intervertebral disc and cartilage regeneration- Current concepts, parallels, and perspectives, Journal of Orthopaedic Research, 35, (1), 2017, p8 - 22, Review Article, PUBLISHED  TARA - Full Text
Naqvi, S.M. and Buckley, C.T. , Bone Marrow Stem Cells in Response to Intervertebral Disc-Like Matrix Acidity and Oxygen Concentration - Implications for Cell-Based Regenerative Therapy, Spine, 41, (9), 2016, p743 - 750, Journal Article, PUBLISHED  TARA - Full Text
Naqvi S.M., Vedicherla S.V., Gansau J, McIntyre T, Doherty M and Buckley C.T., Living Cell Factories- Electrosprayed Microcapsules and Microcarriers for Minimally Invasive Delivery, Advanced Materials , 28, (27), 2016, p5662-5671-, Journal Article, PUBLISHED  TARA - Full Text
  

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Buckley C.T. , Cellular microencapsulation and microenvironmental challenges for intervertebral disc regeneration, AOSpine Masters Symposium-Novel and Emerging Technologies in Translational Medicine , Bern, Switzerland, 22 - 23 September , 2017, Invited Talk, ACCEPTED
Buckley C.T. , Engineering solutions to regenerate-Injectable cellular microcapsules for intervertebral disc repair. Cell Matrix and Regenerative Medicince (CMRM) Seminar Series, Cell Matrix and Regenerative Medicince (CMRM) Seminar Series, Manchester University, UK, 9th June , 2017, Wellcome Trust Centre for Cell-Matrix Research and the Division of Cell Matrix Biology and Regenerative Medicine, Invited Talk, ACCEPTED
Buckley C.T. , Cells and Injectable Biomaterials - Engineering for the Disc Microenvironment, Orthopaedic Research Society Spine Section Meeting, San Diego Convention Center, USA, March 19th, 2017, Invited Talk, PRESENTED
Irwin, P.P. and Buckley, C.T. , Glucose mapping of bovine intervertebral disc organ culture models. An experimental and numerical analysis. , Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, 2017, Poster, PRESENTED
Mandal, P. and Buckley, C.T., Comparison of bone marrow stem cells and nasal chondrocytes for nucleus pulposus regeneration, Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, 2017, Poster, PRESENTED
Buckley C.T. , Regenerating the Intervertebral Disc- Biomaterial Strategies, Stem Cells and Microenvironmental Effects, Icahn School of Medicine at Mount Sinai, New York, USA, Nov , 2014, Invited Talk, PRESENTED
Buckley C.T. , SCIENCE & SPORTS INJURIES- How tissue engineering will reduce the need for complex surgery?, A World of Science in Sport, Public Lecture, Global Room, Trinity College Dublin, Jul , 2014, Invited Talk, PRESENTED
Buckley C.T. , Regenerative Medicine & Tissue Engineering, Trinity Centre for Bioengineering Winter Symposium, Trinity College Dublin, Dec , 2010, Invited Talk, PRESENTED
Buckley C.T. , Mesenchymal Stem Cell Based Therapies for Articular Cartilage Repair, Mesenchymal Stem Cell Group Seminar Series, University of Leeds, July , 2010, Invited Talk, PRESENTED
Buckley C.T. , Articular Cartilage Repair- Biophysical and Biochemical Environments for Mesenchymal Stem Cell Based Therapies, Seminar Series, University of Sheffield, UK, May , 2010, Invited Talk, PRESENTED

  

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Award Date
Science Foundation Ireland, Career Development Award- Principal Investigator 2016
Irish Research Council (IRC) New foundations Award- Principal Investigator 2014
Global Medical Discovery Series. Contribution- Principal Investigator 2014
Engineers Ireland Biomedical Research Medal- Co-Investigator 2014
Best overall MSc Thesis in Bioengineering. Principal Investigator 2012-2016
Engineers Ireland Biomedical Research Medal. Co-Investigator 2012
European Society of Biomechanics S.M. Perren Award. Co-Investigator 2012
Science Foundation Ireland Travel Fellowship- Investigator 2009
The overall goal of my laboratory is to develop novel biomaterial and cell based strategies to regenerate or repair damaged tissues and restore biomechanical function using minimal invasive strategies (MIS). *Intervertebral Disc, Cartilage, Nerve Tissue Engineering *Cellular Microencapsulation for Therapeutic Regeneration *Cryopreservation strategies *Biomimetics & Decellularisation of Native Tissues as Scaffold Matrices *Scaffold Fabrication Technology (Injectable Biomaterials, Bio Printing) *Strategies for Innovative Intraoperative Clinical Intervention *Bioreactor Systems and Biophysical Stimulation *3D Printing of Medical Devices