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Dr. Matthew Campbell

Assistant Professor (Genetics)

Assistant Professor (Trinity Inst. of Neurosciences (TCIN))

  AGE-RELATED MACULOPATHY   Alzheimer's Disease   BLOOD-BRAIN-BARRIER   Cell signalling, proliferation & differentiation   Cellular Biology   ENDOTHELIAL CELLS   Genetics   INFLAMMATION   Molecular Biology   Molecular Genetics   Neurobiology   neurodegeneration   Neuroscience   siRNA technology   TIGHT JUNCTIONS   Transgenics   Vision
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Member of International Society for Eye Research. 2010-present: International Brain Barriers Society (IBBS). 2014 Present
Greenwood, J. and Hammarlund-Udenaes, M. and Jones, H.C. and Stitt, A.W. and Vandenbroucke, R.E. and Romero, I.A. and Campbell, M. and Fricker, G. and Brodin, B. and Manninga, H. and Gaillard, P.J. and Schwaninger, M. and Webster, C. and Wicher, K.B. and Khrestchatisky, M., Correction: Current research into brain barriers and the delivery of therapeutics for neurological diseases: A report on CNS barrier congress London, UK, 2017 [Fluids Barriers CNS 14, (2017) (31)] DOI: 10.1186/s12987-017-0079-9, Fluids and Barriers of the CNS, 15, (1), 2018, p3-, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Campbell, M. and Cassidy, P.S. and O'Callaghan, J. and Crosbie, D.E. and Humphries, P., Manipulating ocular endothelial tight junctions: Applications in treatment of retinal disease pathology and ocular hypertension, Progress in Retinal and Eye Research, 62, 2018, p120-133 , Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Kealy, J. and Greene, C. and Campbell, M., Blood-brain barrier regulation in psychiatric disorders, Neuroscience Letters, 2018, Notes: [cited By 0; Article in Press], Journal Article, PUBLISHED  TARA - Full Text  DOI
Doherty, C.P., O'Keeffe. E., Keaney, J., Lawlor, B.A., Coen, R.F., Farrell, M., Campbell, M., Neuropolypathology as a result of severe traumatic brain injury? , Clinical Neuropathology, 2018, p1 - 12, Journal Article, IN_PRESS
Menard, C. and Pfau, M.L. and Hodes, G.E. and Kana, V. and Wang, V.X. and Bouchard, S. and Takahashi, A. and Flanigan, M.E. and Aleyasin, H. and Leclair, K.B. and Janssen, W.G. and Labonté, B. and Parise, E.M. and Lorsch, Z.S. and Golden, S.A. and Heshmati, M. and Tamminga, C. and Turecki, G. and Campbell, M. and Fayad, Z.A. and Tang, C.Y. and Merad, M. and Russo, S.J., Social stress induces neurovascular pathology promoting depression, Nature Neuroscience, 20, (12), 2017, p1752-1760 , Notes: [cited By 3], Journal Article, PUBLISHED  DOI
Theodoropoulou S, Copland D.A, Liu J, Wu J, Gardner P.J, Ozaki E, Doyle S.L, Campbell M, Dick A.D, Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye, Journal of Pathology, 241, (1), 2017, p45 - 56, Notes: [Export Date: 21 February 2017], Journal Article, PUBLISHED  DOI  URL
Shah T.M, Gupta S.M, Chatterjee P, Campbell M, Martins R.N, Beta-amyloid sequelae in the eye: a critical review on its diagnostic significance and clinical relevance in Alzheimer†s disease, Molecular Psychiatry, 22, 2017, p353-363-, Journal Article, PUBLISHED  DOI  URL
C Greene, J Kealy, M M Humphries, Y Gong, J Hou, N Hudson, L M Cassidy, R Martiniano, V Shashi, S R Hooper, G A Grant, P F Kenna, K Norris, C K Callaghan, M dN Islam, S M O'Mara, Z Najda, S G Campbell, J S Pachter, J Thomas, N M Williams, P Humphries, K C Murphy, M Campbell, Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia, Molecular Psychiatry, 2017, Notes: [C Greene and J Kealy are joint first authors], Journal Article, PUBLISHED  DOI
Tam L.C.S, Reina-Torres E, Sherwood J.M, Cassidy P.S, Crosbie D.E, LÃ"tjen-Drecoll E, FlÃ"gel-Koch C, Perkumas K, Humphries M.M, Kiang A.-S, O'Callaghan J, Callanan J.J, Read A.T, Ethier C.R, O'Brien C, Lawrence M, Campbell M, Stamer W.D, Overby D.R, Humphries P, Enhancement of outflow facility in the murine eye by targeting selected tight-junctions of Schlemm's canal endothelia, Scientific Reports, 7, 2017, p40717-, Notes: [Export Date: 20 February 2017], Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
O'Callaghan, J. and Crosbie, D.E. and Cassidy, P.S. and Sherwood, J.M. and FlÃŒgel-Koch, C. and LÃŒtjen-Drecoll, E. and Humphries, M.M. and Reina-Torres, E. and Wallace, D. and Kiang, A.-S. and Campbell, M. and Stamer, W.D. and Overby, D.R. and O'Brien, C. and Tam, L.C.S. and Humphries, P., Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma, Human Molecular Genetics, 26, (7), 2017, p1230-1246 , Notes: [cited By 6], Journal Article, PUBLISHED  DOI

Page 1 of 8
1. K Mulfaul, E Ozaki, K Brennan, M Campbell, S Doyle, Investigating a role for Toll like receptor signaling in the pathogenesis of Age Related Macular Degeneration (AMD). , Investigative Ophthalmology & Visual Science, , ARVO, Seattle, 57 (12), (5010-5010), 2016, Conference Paper, PUBLISHED
10. C Doherty, E Wallace, M Campbell, P Humphries, Evaluation of an Acute RNAi-Mediated Therapeutic for Visual Dysfunction Associated with Traumatic Brain Injury., Neurology 2012, SAINT JAMES HOSPITAL DUBLIN (IRELAND), 2012, Conference Paper, PUBLISHED
12. GA Grant, C Wilson, M Campbell, S Li, P Humphries, A Johnson, Reversible Opening of the Blood-brain Barrier by Targeted Suppression of Claudin 5 To Enhance Drug Delivery into Brain Tumors. , Annals of Neurology , 2012, Conference Paper, PUBLISHED
Brankin B, Campbell M, Humphries M, Kennan A, Kenna P, Humphries P, Zonulas occluden 1 expression in retinas from Rho-/-C129 mice, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 45, (Suppl. 2), 2004, ppU179 - U179, Meeting Abstract, PUBLISHED


Award Date
Roche Research Award, Smurfit Institute of Genetics 2010
Fighting Blindness Ireland Research Scholarship 2002
Irish Research Council Laureate Award. 2018
Association for Ocular Pharmacology and Therapeutics, National Eye Institute (NEI) award 2015
Association for Research in Vision and Ophthalmology, NEI travel Award 2015
Genentech/ARVO fellowship in recognition of my research on AMD 2015
Science Foundation Ireland, President of Ireland Young Researcher Award (PIYRA) 2013
"Pro-Retina" travel award for XVth International Symposium on Retinal Degenerations 2012
Appointed Senior Research Fellow, TCD 2012