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Dr. Andrew Knox

Adjunct Assistant Professor (Biochemistry)

 

Adjunct Assistant Professor (Sch Office - Biochemistry & Immunology)


  ANTIMICROBIAL PEPTIDES   BIOACTIVE PEPTIDES   Bioinformatics & Computational Biology Techniques   Computational Biology   Computational chemistry and modelling   Computer assisted drug design   computer-assisted language learning   Drug Design   Oral administration of macromolecules, peptides and proteins   PEPTIDE   PEPTIDE DRUGS   PEPTIDE STRUCTURE   Protein Design and Engineering   PROTEIN PURIFICATION   structural biology   STRUCTURAL PROTEINS   Virtual Screening
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Full Membership of the Biochemical Society
O'Boyle, NM, Barrett, I, Greene, LM, Carr, M, Fayne, D, Twamley, B, Knox, AJS, Keely, NO, Zisterer, DM, Meegan, MJ, Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity, Journal of Medicinal Chemistry, 61, (2), 2018, p514 - 534, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
O'Boyle NM, Barrett I, Greene LM, Carr M, Fayne D, Twamley B, Knox AJS, Keely NO, Zisterer DM, Meegan MJ., Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity., Journal of medicinal chemistry, 2017, Journal Article, PUBLISHED  DOI
Doherty W, Adler N, Knox A, Nolan D, McGouran J, Nikalje A.P, Lokwani D, Sarkate A, Evans P, Synthesis and Evaluation of 1,2,3-Triazole-Containing Vinyl and Allyl Sulfones as Anti-Trypanosomal Agents, European Journal of Organic Chemistry, 2017, (1), 2017, p175 - 185, Notes: [Export Date: 27 January 2017], Journal Article, PUBLISHED  DOI  URL
Carr M, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ., Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells., Journal of Enzyme Inhibition and Medicinal Chemistry, 31, 2016, p117-130 , Journal Article, PUBLISHED  DOI
O'Boyle, NM, Pollock, JK, Carr, M, Knox, AJS, Nathwani, SM, Wang, S, Caboni, L, Zisterer, DM, Meegan, MJ, β-Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand, Journal of Medicinal Chemistry, 57, (22), 2014, p9370 - 9382, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Doherty W, James J, Evans P, Martin L, Adler N, Nolan D, Knox A, Preparation, anti-trypanosomal activity and localisation of a series of dipeptide-based vinyl sulfones., Organic & biomolecular chemistry, 12, (38), 2014, p7561-71 , Journal Article, PUBLISHED  DOI
O'Boyle NM, Pollock JK, Carr M, Knox AJ, Nathwani SM, Wang S, Caboni L, Zisterer DM, Meegan MJ., β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand., Journal of medicinal chemistry, 57, (22), 2014, p9370-9382 , Journal Article, PUBLISHED  DOI
O'Boyle, N.M., Pollock, J.K., Carr, M., Knox, A.J.S., Nathwani, S.M., Wang, S., Caboni, L., Zisterer, D.M., Meegan, M.J., ß-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand, Journal of Medicinal Chemistry, 57, (22), 2014, p9370-9382 , Journal Article, PUBLISHED
Doherty W, James J, Evans P, Martin L, Adler N, Nolan D, Knox A. , Preparation, anti-trypanosomal activity and localisation of a series of dipeptide-based vinyl sulfones., Organic & Biomolecular Chemistry, 12, (38), 2014, p12(38):756 - 7571, Journal Article, PUBLISHED
Dunny E, Doherty W, Evans P, Malthouse JP, Nolan D, Knox AJ, Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation., Journal of medicinal chemistry, 56, (17), 2013, p6638-50 , Journal Article, PUBLISHED  DOI
  

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